Structure of PDB 2j7n Chain B Binding Site BS01

Receptor Information
>2j7n Chain B (length=931) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HAPVVAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLEDESLGLK
YDPSWSTARDVTDIWKTLYRLDAFRGKPFPEKPPNDVFVTAMTGNFESKG
SAVVLSAVLDYNPDNSPTAPLYLVKLKPLMFEQGCRLTRRFGPDRFFEIL
IPSPTSTSPSVPPVVSKQPAAVEEVIQWLTMGQHSLVGRQWRAFFAKDAG
YIIKERVHFFAETGITFRPDVQRTEFKVSQMLDWLLQLDNNTWQPHLKLF
SRIQLGLSKTYAIMTLEPHQIRHHKTDLLSPSGTGEVMNDGVGRMSRSVA
KRIRDVLGLGDVPSAVQGRFGSAKGMWVIDVDDTGDEDWIETYPSQRKWE
CDFVDKHQRTLEVRSVASELKSAGLNLQLLPVLEDRARDKVKMRQAIGDR
LINDLQRQFSEQKHALNRPVEFRQWVYESYSSRATRVSHGRVPFLAGLPD
SQEETLNFLMNSGFDPKKQKYLQDIAWDLQKRKCDTLKSKLNIRVGRSAY
IYMIADFWGVLEENEVHVGFSSKFRDEEESFTLLSDCDVLVARSPAHFPS
DIQRVRAVFKPELHSLKDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDP
EIVDGFVNAEMPLEPDLSRYLKKDKTTFKQLMASHGTGSAAKEQTTYDMI
QKSFHFALQPNFLGMCTNYKERLCYINNSVSNKPAIILSSLVGNLVDQSK
QGIVFNEASWAQLRRELLGGALSLPDPMYKSDSWLGRGEPTHIIDYLKFS
IARPAIDKELEAFHNAMKAAKDTEDGAHFWDPDLASYYTFFKEISDKSRS
SALLFTTLKNRIGEVEKEYGRDPYPVRVNQVYEKWCAITPSKVIRLLELS
FLADREMNTWALLRASTAFKLYYHKSPKFVWQMAGRQLAYIKAQMTSRPG
EGAPALMTAFMYAGLMPDKKFTKQYVARLEG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2j7n Chain B Residue 3374 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2j7n The Structure of an Rnai Polymerase Links RNA Silencing and Transcription.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D1007 D1009 D1011
Binding residue
(residue number reindexed from 1)		D588 D590 D592
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:2j7n, PDBe:2j7n, PDBj:2j7n
PDBsum2j7n
PubMed17147473
UniProtQ9Y7G6

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