Structure of PDB 2itb Chain B Binding Site BS01

Receptor Information

>2itb Chain B (length=198) Species: 160488 (Pseudomonas putida KT2440) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IPEIDAFLGCPTPDAWIEAALADQETLLIDHKNCEFKAASTALSLIAKYN
THLDLINMMSRLAREELVHHEQVLRLMKRRGVPLRPVSAGRYASGLRRLV
RAHEPVKLVDTLVVGAFIEARSCERFAALVPHLDEELGRFYHGLLKSEAR
HYQGYLKLAHNYGDEADIARCVELVRAAEMELIQSPDQELRFHSGIPQ

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

2itb Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2itb Crystal structure of putative tRNA-(ms(2)io(6)a)-hydroxylase (NP_744337.1) from Pseudomonas Putida KT2440 at 2.05 A resolution
Resolution	2.05 Å
Binding residue (original residue number in PDB)	E38 E69 H72 E151
Binding residue (residue number reindexed from 1)	E35 E66 H69 E148
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.99.69: tRNA 2-(methylsulfanyl)-N(6)-isopentenyladenosine(37) hydroxylase.

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0045301	tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006400	tRNA modification
GO:0008033	tRNA processing

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Molecular Function

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Biological Process

External links

PDB	RCSB:2itb, PDBe:2itb, PDBj:2itb
PDBsum	2itb
PubMed
UniProt	Q88KV1\|MIAE_PSEPK tRNA 2-(methylsulfanyl)-N(6)-isopentenyladenosine(37) hydroxylase (Gene Name=miaE)

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