Structure of PDB 2iep Chain B Binding Site BS01

Receptor Information
>2iep Chain B (length=187) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTR
YSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKIT
RPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSALRENSRIAVLESGS
LRIHNVQKEDAGQYRCVAKNSLGTAYSKLVKLEVEVF
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain2iep Chain B Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2iep Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK
Resolution2.205 Å
Binding residue
(original residue number in PDB)		T62 K65 E110
Binding residue
(residue number reindexed from 1)		T38 K41 E86
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
External links
PDB RCSB:2iep, PDBe:2iep, PDBj:2iep
PDBsum2iep
PubMed17011580
UniProtQ62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase (Gene Name=Musk)

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