Structure of PDB 2id4 Chain B Binding Site BS01

Receptor Information
>2id4 Chain B (length=479) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVA
AIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEI
AAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSC
SWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDN
CNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSGEYIHSS
DINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGL
EKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLP
TLYVSQSTNSTEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGT
TTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIK
VKTTENGHRIDFHSWRLKLFGESIDSSKT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2id4 Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D176 H213 L246 I250 E255 S272 W273 G274 P275 D277 N314 S385
Binding residue
(residue number reindexed from 1)		D55 H92 L125 I129 E134 S151 W152 G153 P154 D156 N193 S264
Enzymatic activity
Catalytic site (original residue number in PDB) D175 H213 N314 S385
Catalytic site (residue number reindexed from 1) D54 H92 N193 S264
Enzyme Commision number 3.4.21.61: kexin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2id4, PDBe:2id4, PDBj:2id4
PDBsum2id4
PubMed17426142
UniProtP13134|KEX2_YEAST Kexin (Gene Name=KEX2)

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