Structure of PDB 2icw Chain B Binding Site BS01

Receptor Information

>2icw Chain B (length=184) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPSKTNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQ
TLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA

Ligand information

>2icw Chain C (length=13) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PKYVKQNTLKLAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2icw Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Resolution	2.41 Å
Binding residue (original residue number in PDB)	W9 L11 F13 P56 D57 W61 L67 Q70 R71 Y78 H81 N82
Binding residue (residue number reindexed from 1)	W9 L11 F13 P56 D57 W61 L67 Q70 R71 Y78 H81 N82

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:2icw, PDBe:2icw, PDBj:2icw
PDBsum	2icw
PubMed	17220897
UniProt	P01911\|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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