Structure of PDB 2hv8 Chain B Binding Site BS01

Receptor Information
>2hv8 Chain B (length=169) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVD
GKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWL
KELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSAL
DSTNVEAAFQTILTEIYRI
Ligand information
Ligand ID2ME
InChIInChI=1S/C3H8O/c1-3-4-2/h3H2,1-2H3
InChIKeyXOBKSJJDNFUZPF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04methoxyethane
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCOC
FormulaC3 H8 O
NameMETHOXYETHANE
ChEMBL
DrugBank
ZINCZINC000002034870
PDB chain2hv8 Chain B Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2hv8 Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
Resolution1.86 Å
Binding residue
(original residue number in PDB)		R129 R132
Binding residue
(residue number reindexed from 1)		R123 R126
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2hv8, PDBe:2hv8, PDBj:2hv8
PDBsum2hv8
PubMed17007872
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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