Structure of PDB 2hpc Chain B Binding Site BS01

Receptor Information
>2hpc Chain B (length=307) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVS
CNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWT
VIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKIS
QLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAG
NALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGG
GWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
SMKIRPF
Ligand information
Receptor-Ligand Complex Structure
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PDB2hpc ?
Resolution2.9 Å
Binding residue
(original residue number in PDB)
M367 W385 E397 R406 C407 H408 T431 D432 M438
Binding residue
(residue number reindexed from 1)
M217 W235 E247 R256 C257 H258 T281 D282 M288
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2hpc, PDBe:2hpc, PDBj:2hpc
PDBsum2hpc
PubMed
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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