Structure of PDB 2hof Chain B Binding Site BS01

Receptor Information
>2hof Chain B (length=316) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTATLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hof Synapsis of loxP sites by Cre recombinase.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K43 M44 S47 R50 R81 L83 A84 K86 T87 Q90 R118 K132 R159 R173 R241 V242 K244 S257 R259 A260 R282 W315 T316 N317
Binding residue
(residue number reindexed from 1)		K24 M25 S28 R31 R62 L64 A65 K67 T68 Q71 R99 K113 R140 R154 R222 V223 K225 S238 R240 A241 R263 W296 T297 N298
Binding affinityPDBbind-CN: Kd=8.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:2hof, PDBe:2hof, PDBj:2hof
PDBsum2hof
PubMed17573343
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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