Structure of PDB 2hih Chain B Binding Site BS01

Receptor Information
>2hih Chain B (length=386) Species: 1284 (Staphylococcus hyicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVQNPENPKNKDPFVFVHGFTGFVGEVAAKGENYWGGTKANLRNHLRKAG
YETYEASVSALASNHERAVELYYYLKGGRVDYGAAHSEKYGHERYGKTYE
GVLKDWKPGHPVHFIGHSMGGQTIRLLEHYLRFGDKAEIAYQQQHGGIIS
ELFKGGQDNMVTSITTIATPHNGTHASDDIGNTPTIRNILYSFAQMSSHL
GTIDFGMDHWGFKRKDGESLTDYNKRIAESKIWDSEDTGLYDLTREGAEK
INQKTELNPNIYYKTYTGVATHETQLGKHIADLGMEFTKILTGNYIGSVD
DILWRPNDGLVSEISSQHPSDEKNISVDENSELHKGTWQVMPTMKGWDHS
DFIGNDALDTKHSAIELTNFYHSISDYLMRIEKAES
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2hih Chain B Residue 1601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hih Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		E72 H92 H98 D243
Binding residue
(residue number reindexed from 1)		E66 H86 H92 D237
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
3.1.1.32: phospholipase A1.
External links
PDB RCSB:2hih, PDBe:2hih, PDBj:2hih
PDBsum2hih
PubMed17582438
UniProtP04635|LIP_STAHY Lipase (Gene Name=lip)

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