Structure of PDB 2h8c Chain B Binding Site BS01

Receptor Information
>2h8c Chain B (length=116) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGL
AMPVKIRIECHMPDRRRRNLDNLQKAAFDALTKAGFWLDDAQVVDYRVVK
MPVTKGGRLELTITEM
Ligand information
Receptor-Ligand Complex Structure
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PDB2h8c RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
N15 R67 R68 R69 N70 N73
Binding residue
(residue number reindexed from 1)
N14 R66 R67 R68 N69 N72
Enzymatic activity
Enzyme Commision number 3.1.21.10: crossover junction endodeoxyribonuclease.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0004519 endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function

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Biological Process
External links
PDB RCSB:2h8c, PDBe:2h8c, PDBj:2h8c
PDBsum2h8c
PubMed17028102
UniProtP0AG74|RUSA_ECOLI Crossover junction endodeoxyribonuclease RusA (Gene Name=rusA)

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