Structure of PDB 2h57 Chain B Binding Site BS01

Receptor Information
>2h57 Chain B (length=167) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEVHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIGFSIEKFKSSSLSF
TVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNH
PDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLENIKDKPWHICASDAI
KGEGLQEGVDWLQDQIQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2h57 Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2h57 Crystal structure of human ADP-ribosylation factor-like 6 (CASP Target)
Resolution2.0 Å
Binding residue
(original residue number in PDB)		T31 T50
Binding residue
(residue number reindexed from 1)		T16 T35
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q73
Catalytic site (residue number reindexed from 1) Q58
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0005543 phospholipid binding
GO:0046872 metal ion binding
Biological Process
GO:0006612 protein targeting to membrane
GO:0006886 intracellular protein transport
GO:0007368 determination of left/right symmetry
GO:0007601 visual perception
GO:0015031 protein transport
GO:0016055 Wnt signaling pathway
GO:0016192 vesicle-mediated transport
GO:0030030 cell projection organization
GO:0032402 melanosome transport
GO:0051258 protein polymerization
GO:0060271 cilium assembly
GO:0061512 protein localization to cilium
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005879 axonemal microtubule
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0005930 axoneme
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0030117 membrane coat
GO:0042995 cell projection
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2h57, PDBe:2h57, PDBj:2h57
PDBsum2h57
PubMed
UniProtQ9H0F7|ARL6_HUMAN ADP-ribosylation factor-like protein 6 (Gene Name=ARL6)

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