Structure of PDB 2gpp Chain B Binding Site BS01
Receptor Information
>2gpp Chain B (length=224) Species:
9606
(Homo sapiens) [
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PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGW
AKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIM
DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHI
EDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAV
QHFYNIKLEGKVPMHKLFLEMLEA
Ligand information
>2gpp Chain D (length=13) Species:
9606
(Homo sapiens) [
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SLLLHLLKSQTIP
Receptor-Ligand Complex Structure
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PDB
2gpp
X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
I280 G281 K284 M298 K448 L449 E452
Binding residue
(residue number reindexed from 1)
I48 G49 K52 M66 K216 L217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2gpp
,
PDBe:2gpp
,
PDBj:2gpp
PDBsum
2gpp
PubMed
16990259
UniProt
P62508
|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)
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