Structure of PDB 2gmt Chain B Binding Site BS01

Receptor Information
>2gmt Chain B (length=131) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2gmt Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		P24 S26 W27 P28 Q116 A120 C122
Binding residue
(residue number reindexed from 1)		P9 S11 W12 P13 Q101 A105 C107
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102
Catalytic site (residue number reindexed from 1) H42 D87
Enzyme Commision number 3.4.21.1: chymotrypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2gmt, PDBe:2gmt, PDBj:2gmt
PDBsum2gmt
PubMed7947790
UniProtP00766|CTRA_BOVIN Chymotrypsinogen A

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