Structure of PDB 2glj Chain B Binding Site BS01

Receptor Information
>2glj Chain B (length=456) Species: 1488 (Clostridium acetobutylicum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLKEYKNAWDKYDDKQLKEVFALGDRFKNFISNCKTERECVTELIKTAEK
SGYRNIEDILAKGETLKEGDKVYANNRGKGLIMFLIGKEPLYTGFKILGA
HIDSPRLDLKQNPLYEDTDLAMLETHYYGGIKKYQWVTLPLAIHGVIVKK
DGTIVNVCVGEDDNDPVFGVSDILVHLASEQLEKKASKVIEGEDLNILIG
SIPLKDGEEKQKVKHNIMKILNEKYDISEEDFVSAELEIVPAGKARDYGF
DRSMVMGYGQDDRICAYTSFEAMLEMKNAKKTCITILVDKEEVGSIGATG
MQSKFFENTVADIMSDELKLRKALYNSEMLSSDVSAAFDPNYPNVMEKRN
SAYLGKGIVFNKYTGSRGKSGCNDANPEYIAELRRILSKESVNWQTAELG
KVDQGGGGTIAYILAEYGMQVIDCGVALLNMHAPWEISSKADIYETKNGY
SAFLNN
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2glj Chain B Residue 6003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2glj crystal structure of aminopeptidase I from Clostridium acetobutylicum
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D265 E295 E296 H441
Binding residue
(residue number reindexed from 1)		D261 E291 E292 H432
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:2glj, PDBe:2glj, PDBj:2glj
PDBsum2glj
PubMed
UniProtQ97K30|APEA_CLOAB Probable M18 family aminopeptidase 1 (Gene Name=apeA)

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