Structure of PDB 2gil Chain B Binding Site BS01

Receptor Information
>2gil Chain B (length=162) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTV
RLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVR
TERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYN
VKQLFRRVAAAL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2gil Chain B Residue 2201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2gil Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution
Resolution1.82 Å
Binding residue
(original residue number in PDB)		T27 T45
Binding residue
(residue number reindexed from 1)		T15 T33
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q72
Catalytic site (residue number reindexed from 1) Q60
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2gil, PDBe:2gil, PDBj:2gil
PDBsum2gil
PubMed16332443
UniProtP20340|RAB6A_HUMAN Ras-related protein Rab-6A (Gene Name=RAB6A)

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