Structure of PDB 2gct Chain B Binding Site BS01

Receptor Information
>2gct Chain B (length=131) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2gct Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		I16 E20 V23 S26 W27 P28 Q116 A120 C122
Binding residue
(residue number reindexed from 1)		I1 E5 V8 S11 W12 P13 Q101 A105 C107
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102
Catalytic site (residue number reindexed from 1) H42 D87
Enzyme Commision number 3.4.21.1: chymotrypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2gct, PDBe:2gct, PDBj:2gct
PDBsum2gct
PubMed1888717
UniProtP00766|CTRA_BOVIN Chymotrypsinogen A

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