Structure of PDB 2g44 Chain B Binding Site BS01
Receptor Information
>2g44 Chain B (length=237) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAP
Ligand information
>2g44 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2g44
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity
Resolution
2.65 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 L67 V71 D223 L224 E227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2g44
,
PDBe:2g44
,
PDBj:2g44
PDBsum
2g44
PubMed
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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