Structure of PDB 2fse Chain B Binding Site BS01

Receptor Information
>2fse Chain B (length=186) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELG
RPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPTVTVYPT
KTQPLQHHNLLVCSVSDFYPGNIEVRWFRNGKEEETGIVSTGLVRNGDWT
FQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fse Crystallographic Structure of a Rheumatoid Arthritis MHC Susceptibility Allele, HLA-DR1 (DRB1*0101), Complexed with the Immunodominant Determinant of Human Type II Collagen.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F13 E28 D57 Y60 W61 R71 Y78 N82 V85
Binding residue
(residue number reindexed from 1)		F9 E24 D53 Y56 W57 R67 Y74 N78 V81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2fse, PDBe:2fse, PDBj:2fse
PDBsum2fse
PubMed16951351
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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