Structure of PDB 2fmt Chain B Binding Site BS01

Receptor Information
>2fmt Chain B (length=314) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSP
VKVLAEEKGLPVFQPVSLRPQENQQLVAELQADVMVVVAYGLILPKAVLE
MPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDM
LYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETL
VTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKA
SVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLL
NSRREWFVPGNRLV
Ligand information
>2fmt Chain D (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgggguggagcagccugguagcucgucgggcucauaacccgaagaucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB2fmt Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T11 P12 P39 A40 G41 R42 G43 K44 A89 G91 A120 L207 K209 W233 K246 G290 K291 M294 D298 N301 S302 R303 R304
Binding residue
(residue number reindexed from 1)		T11 P12 P39 A40 G41 R42 G43 K44 A89 G91 A120 L207 K209 W233 K246 G290 K291 M294 D298 N301 S302 R303 R304
Enzymatic activity
Enzyme Commision number 2.1.2.9: methionyl-tRNA formyltransferase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0019988 charged-tRNA amino acid modification
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:2fmt, PDBe:2fmt, PDBj:2fmt
PDBsum2fmt
PubMed9843487
UniProtP23882|FMT_ECOLI Methionyl-tRNA formyltransferase (Gene Name=fmt)

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