Structure of PDB 2flh Chain B Binding Site BS01

Receptor Information
>2flh Chain B (length=153) Species: 157791 (Vigna radiata) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVKEFNTQTELSVRLEALWAVLSKDFITVVPKVLPHIVKDVQLIEGDGGV
GTILIFNFLPEVSPSYQREEITEFDESSHEIGLQVIEGGYLSQGLSYYKT
TFKLSEIEEDKTLVNVKISYDHDSDIEEKVTPTKTSQSTLMYLRRLERYL
SNG
Ligand information
Ligand IDZEA
InChIInChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
InChIKeyUZKQTCBAMSWPJD-FARCUNLSSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.5CC(=CCNc1c2c([nH]cn2)ncn1)CO
OpenEye OEToolkits 1.7.5C/C(=C\CNc1c2c([nH]cn2)ncn1)/CO
CACTVS 3.385CC(/CO)=C\CNc1ncnc2[nH]cnc12
CACTVS 3.385CC(CO)=CCNc1ncnc2[nH]cnc12
ACDLabs 10.04n2c1c(ncn1)c(nc2)NC\C=C(/C)CO
FormulaC10 H13 N5 O
Name(2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol;
TRANS-ZEATIN
ChEMBLCHEMBL525239
DrugBankDB11337
ZINCZINC000004492895
PDB chain2flh Chain A Residue 708 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2flh Crystal Structure of Vigna radiata Cytokinin-Specific Binding Protein in Complex with Zeatin.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		A20 D25
Binding residue
(residue number reindexed from 1)		A20 D25
Annotation score4
Binding affinityMOAD: Kd=106uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004864 protein phosphatase inhibitor activity
GO:0010331 gibberellin binding
GO:0010427 abscisic acid binding
GO:0038023 signaling receptor activity
GO:0044373 cytokinin binding
Biological Process
GO:0006952 defense response
GO:0009738 abscisic acid-activated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2flh, PDBe:2flh, PDBj:2flh
PDBsum2flh
PubMed16998071
UniProtA0A1S3THR8|PHBP_VIGRR Phytohormone-binding protein CSBP (Gene Name=CSBP)

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