Structure of PDB 2fh1 Chain B Binding Site BS01

Receptor Information
>2fh1 Chain B (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRQGQIIYNWQ
GAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPM
IIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF
VLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEA
LGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLA
TDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPI
TVVKQGFEPPSFVGWFLGWDDDYW
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2fh1 Chain B Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fh1 Calcium ion exchange in crystalline gelsolin
Resolution1.55 Å
Binding residue
(original residue number in PDB)		G444 D445 E475 T524
Binding residue
(residue number reindexed from 1)		G31 D32 E58 T107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:2fh1, PDBe:2fh1, PDBj:2fh1
PDBsum2fh1
PubMed16466744
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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