Structure of PDB 2fcw Chain B Binding Site BS01

Receptor Information
>2fcw Chain B (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTCSQAEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCN
SSTCIPQLWACDNDPDCEDGSDEWPQRC
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2fcw Chain B Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fcw Structure of an LDLR-RAP Complex Reveals a General Mode for Ligand Recognition by Lipoprotein Receptors
Resolution1.26 Å
Binding residue
(original residue number in PDB)		F105 D108 D110 D112 D118 E119
Binding residue
(residue number reindexed from 1)		F20 D23 D25 D27 D33 E34
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2fcw, PDBe:2fcw, PDBj:2fcw
PDBsum2fcw
PubMed16630895
UniProtP01130|LDLR_HUMAN Low-density lipoprotein receptor (Gene Name=LDLR)

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