Structure of PDB 2f0a Chain B Binding Site BS01

Receptor Information
>2f0a Chain B (length=88) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIITVTLNMEKYNFLGISIVGQSGIYIGSIMKGGAVAADGRIEPGDMLLQ
VNDINFENMSNDDAVRVLRDIVHKPIVLTVAKLEHHHH
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain2f0a Chain B Residue 349 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2f0a Conformational flexibility in the PDZ domain of Dishevelled induced by target binding
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H344 H346
Binding residue
(residue number reindexed from 1)		H86 H88
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

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Biological Process
External links
PDB RCSB:2f0a, PDBe:2f0a, PDBj:2f0a
PDBsum2f0a
PubMed
UniProtP51142|DVL2_XENLA Segment polarity protein dishevelled homolog DVL-2 (Gene Name=dvl2)

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