Structure of PDB 2erx Chain B Binding Site BS01

Receptor Information
>2erx Chain B (length=166) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCSICT
LQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICE
IKSIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKE
LFQELLNLEKRRTVSL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2erx Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2erx Crystal Structure of DiRas2
Resolution1.65 Å
Binding residue
(original residue number in PDB)		S21 T39
Binding residue
(residue number reindexed from 1)		S17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:2erx, PDBe:2erx, PDBj:2erx
PDBsum2erx
PubMed
UniProtQ96HU8|DIRA2_HUMAN GTP-binding protein Di-Ras2 (Gene Name=DIRAS2)

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