Structure of PDB 2ebs Chain B Binding Site BS01

Receptor Information
>2ebs Chain B (length=771) Species: 203496 (Geotrichum sp. M128) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYEFKNVAIGGGGYITGIVAHPKTKDLLYARTDIGGAYRWDAGTSKWIPL
NDFIEAQDMNIMGTESIALDPNNPDRLYLAQGRYVGDEWAAFYVSEDRGQ
SFTIYESPFPMGANDMGRNNGERLAVNPFNSNEVWMGTRTEGIWKSSDRA
KTWTNVTSIPDAFTNGIGYTSVIFDPERNGTIYASATAPQGMYVTHDGGV
SWEPVAGQPSSWLNRTTGAFPDKKPASIAPQPMKVALTPNFLYVTYADYP
GPWGVTFGEVWRQNRTSGAWDDITPRVGNSSPAPYNNQTFPAGGFCGLSV
DATNPNRLVVITLDRDPGPALDSIYLSTDAGATWKDVTQLSSPSNLEGNW
GHPTNAARYKDGTPVPWLDFNNGPQWGGYGAPHGTPGLTKFGWWMSAVLI
DPFNPEHLMYGTGATIWATDTLSRVEKDWAPSWYLQIDGIEENAILSLRS
PKSGAALLSGIGNISGMKHDDLTKPQKMFGAPQFSNLDSIDAAGNFPNVV
VRAGSSGHEYDSACARGAYATDGGDAWTIFPTCPPGMNASHYQGSTIAVD
ASGSQIVWSTKLDEQASGPWYSHDYGKTWSVPAGDLKAQTANVLSDKVQD
GTFYATDGGKFFVSTDGGKSYAAKGAGLVTGTSLMPAVNPWVAGDVWVPV
PEGGLFHSTDFGASFTRVGTANATLVSVGAPKSSAPSAVFIWGTDKPGSD
IGLYRSDDNGSTWTRVNDQEHNYSGPTMIEADPKVYGRVYLGTNGRGIVY
ADLTKSTAKCANGQKGTHCYV
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain2ebs Chain D Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ebs The Structural Basis for the Exo-mode of Action in GH74 Oligoxyloglucan Reducing End-specific Cellobiohydrolase.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D318 G382 A383 W395
Binding residue
(residue number reindexed from 1)		D316 G380 A381 W393
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.150: oligoxyloglucan reducing-end-specific cellobiohydrolase.
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033945 oligoxyloglucan reducing-end-specific cellobiohydrolase activity
Biological Process
GO:0010411 xyloglucan metabolic process
GO:0030245 cellulose catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2ebs, PDBe:2ebs, PDBj:2ebs
PDBsum2ebs
PubMed17498741
UniProtQ8J0D2|CBHRE_GEOS1 Oligoxyloglucan reducing end-specific cellobiohydrolase

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