Structure of PDB 2eb0 Chain B Binding Site BS01

Receptor Information

>2eb0 Chain B (length=307) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRYVVGHKNPDTDSIASAIVLAYFLDCYPARLGDINPETEFVLRKFGVME
PELIESAKGKEIILVDHSEKSQSFDDLEEGKLIAIIDHHKVGLTTTEPIL
YYAKPVGSTATVIAELYFKDAIDLIGGKKKELKPDLAGLLLSAIISDTVL
FKSPTTTDLDKEMAKKLAEIAGISNIEEFGMEILKAKSVVGKLKPEEIIN
MDFKNFDFNGKKVGIGQVEVIDVSEVESKKEDIYKLLEEKLKNEGYDLIV
FLITDIMKEGSEALVVGNKEMFEKAFNVKVEGNSVFLEGVMSRKKQVVPP
LERAYNG

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

2eb0 Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2eb0 Crystal structure of Methanococcus jannaschii inorganic pyrophosphatase
Resolution	2.2 Å
Binding residue (original residue number in PDB)	D13 D66 H88 D147
Binding residue (residue number reindexed from 1)	D13 D66 H88 D147
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.6.1.1: inorganic diphosphatase.

Gene Ontology

	Molecular Function
GO:0004427	inorganic diphosphate phosphatase activity
GO:0016462	pyrophosphatase activity
GO:0016787	hydrolase activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:2eb0, PDBe:2eb0, PDBj:2eb0
PDBsum	2eb0
PubMed
UniProt	Q58025\|PPAC_METJA Manganese-dependent inorganic pyrophosphatase (Gene Name=ppaC)

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