Structure of PDB 2dti Chain B Binding Site BS01

Receptor Information

>2dti Chain B (length=235) Species: 70601 (Pyrococcus horikoshii OT3)

MLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMGHGRLN
RKWESPEGGLWLSIVLSPKVPQKDLPKIVFLGAVGVVETLKEFSIDGRIK
WPNDVLVNYKKIAGVLVEGKGDKIVLGIGLNVNNKVPNGATSMKLELGSE
VPLLSVFRSLITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSF
EGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSLRFL

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 2dti Chain B Residue 1502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2dti Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3
• Resolution: 2.2 Å
• Binding residue (original residue number in PDB): N103 D104
• Binding residue (residue number reindexed from 1): N103 D104
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): R48 K111 R233
• Catalytic site (residue number reindexed from 1): R48 K111 R233
• Enzyme Commision number: 6.3.4.15: biotin--[biotin carboxyl-carrier protein] ligase.

Gene Ontology

Molecular Function

• GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0036211 protein modification process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:2dti, PDBe:2dti, PDBj:2dti
• PDBsum: 2dti
• UniProt: O57883