Structure of PDB 2dcu Chain B Binding Site BS01

Receptor Information
>2dcu Chain B (length=137) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDYYDYEKLLEKAYQELPENVKHHKSRFEVPGALVTIEGNKTIIENFKDI
ADALNRDPQHLLKFLLREIATAGTLEGRRVVLQGRFTPYLIANKLKKYIK
EYVICPVCGSPDTKIIKRDRFHFLKCEACGAETPIQH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2dcu Chain B Residue 3002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2dcu Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		C107 C110 C128 C131
Binding residue
(residue number reindexed from 1)		C105 C108 C126 C129
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:2dcu, PDBe:2dcu, PDBj:2dcu
PDBsum2dcu
PubMed16924118
UniProtQ8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta (Gene Name=eif2b)

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