Structure of PDB 2cua Chain B Binding Site BS01

Receptor Information
>2cua Chain B (length=132) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYTLATHTAGAGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAF
AFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVR
YTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2cua Chain B Residue 172 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cua The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		H117 E119
Binding residue
(residue number reindexed from 1)		H81 E83
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) F86 F88
Catalytic site (residue number reindexed from 1) F50 F52
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0046872 metal ion binding
Biological Process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cua, PDBe:2cua, PDBj:2cua
PDBsum2cua
PubMed10360350
UniProtP98052|COX2_THETH Cytochrome c oxidase subunit 2 (Fragment) (Gene Name=cbaB)

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