Structure of PDB 2cnn Chain B Binding Site BS01

Receptor Information
>2cnn Chain B (length=103) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLK
QYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELY
FYH
Ligand information
Receptor-Ligand Complex Structure
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PDB2cnn Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 W214 F250 F252
Binding residue
(residue number reindexed from 1)		Y30 S31 W32 R33 W40 F76 F78
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2cnn, PDBe:2cnn, PDBj:2cnn
PDBsum2cnn
PubMed16866351
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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