Structure of PDB 2ckl Chain B Binding Site BS01

Receptor Information
>2ckl Chain B (length=96) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTWELSLYELQRTPQEAITDGLEIVSLHSELMCPICLDMLKNTMTTKECL
HRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIY
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ckl Chain B Residue 1115 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ckl Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C67 H69 C87 C90
Binding residue
(residue number reindexed from 1)		C49 H51 C69 C72
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Cellular Component
GO:0000151 ubiquitin ligase complex

View graph for
Cellular Component
External links
PDB RCSB:2ckl, PDBe:2ckl, PDBj:2ckl
PDBsum2ckl
PubMed16710298
UniProtQ9CQJ4|RING2_MOUSE E3 ubiquitin-protein ligase RING2 (Gene Name=Rnf2)

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