Structure of PDB 2cho Chain B Binding Site BS01

Receptor Information
>2cho Chain B (length=639) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLGMLISIGEK
GDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLK
DGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYI
YGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDI
KWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYID
EKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGD
RVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTI
AKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILP
SAAEELECFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDK
ADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEV
LKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPYQPGVKTATRVIK
PLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMNLPLQVKANRVLISPVE
IELDAIYPGENIQINFRLSAGLQKAPVKFVRFFVLTIEK
Ligand information
>2cho Chain D (length=13) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB2cho Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Resolution1.85 Å
Binding residue
(original residue number in PDB)		R679 L680 S681 F691 V692 R693 F694
Binding residue
(residue number reindexed from 1)		R617 L618 S619 F629 V630 R631 F632
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Gene Ontology
Molecular Function
GO:0015929 hexosaminidase activity
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006517 protein deglycosylation
GO:1901135 carbohydrate derivative metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2cho, PDBe:2cho, PDBj:2cho
PDBsum2cho
PubMed16565725
UniProtQ89ZI2|OGA_BACTN O-GlcNAcase BT_4395 (Gene Name=BT_4395)

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