Structure of PDB 2chn Chain B Binding Site BS01

Receptor Information
>2chn Chain B (length=639) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLGMLISIGEK
GDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLK
DGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYI
YGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDI
KWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYID
EKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGD
RVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTI
AKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILP
SAAEELECFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDK
ADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEV
LKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPYQPGVKTATRVIK
PLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMNLPLQVKANRVLISPVE
IELDAIYPGENIQINFRLSAGLQKAPVKFVRFFVLTIEK
Ligand information
>2chn Chain D (length=12) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2chn Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Resolution1.95 Å
Binding residue
(original residue number in PDB)		S681 F691 V692 R693 F694
Binding residue
(residue number reindexed from 1)		S619 F629 V630 R631 F632
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Gene Ontology
Molecular Function
GO:0015929 hexosaminidase activity
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006517 protein deglycosylation
GO:1901135 carbohydrate derivative metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2chn, PDBe:2chn, PDBj:2chn
PDBsum2chn
PubMed16565725
UniProtQ89ZI2|OGA_BACTN O-GlcNAcase BT_4395 (Gene Name=BT_4395)

[Back to BioLiP]