Structure of PDB 2cci Chain B Binding Site BS01

Receptor Information
>2cci Chain B (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2cci The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M210 W217 E220 E224 R250 L253 Q254 I270 E277 Y280 I281 T282 D283 T285
Binding residue
(residue number reindexed from 1)		M36 W43 E46 E50 R76 L79 Q80 I96 E103 Y106 I107 T108 D109 T111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2cci, PDBe:2cci, PDBj:2cci
PDBsum2cci
PubMed16707497
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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