Structure of PDB 2cch Chain B Binding Site BS01

Receptor Information
>2cch Chain B (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVG
EEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP
PEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ
QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSW
PESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVS
LLNPPETLNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2cch The Role of the Phospho-Cdk2/Cyclin a Recruitment Site in Substrate Recognition
Resolution1.7 Å
Binding residue
(original residue number in PDB)		M210 I213 W217 E220 E224 R250 Q254 E277 Y280 I281 T282 D283 T285
Binding residue
(residue number reindexed from 1)		M38 I41 W45 E48 E52 R78 Q82 E105 Y108 I109 T110 D111 T113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2cch, PDBe:2cch, PDBj:2cch
PDBsum2cch
PubMed16707497
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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