Structure of PDB 2c50 Chain B Binding Site BS01

Receptor Information
>2c50 Chain B (length=129) Species: 12022 (Escherichia phage MS2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASNFTQFVLVDNGGTGDVTVAPSNFANGVAEWISSNSRSQAYKVTCSVRQ
SSAQNRKYTIKVEVPKVATQTVGGVELPVAAWRSYLNMELTIPIFATNSD
CELIVKAMQGLLKDGNPIPSAIAANSGIY
Ligand information
Receptor-Ligand Complex Structure
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PDB2c50 Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		T45 S47 R49 S51 S52 N55 K57 T59 K61
Binding residue
(residue number reindexed from 1)		T45 S47 R49 S51 S52 N55 K57 T59 K61
Binding affinityPDBbind-CN: Kd=0.06nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0042802 identical protein binding
Biological Process
GO:0006417 regulation of translation
GO:1904972 negative regulation of viral translation
Cellular Component
GO:0019028 viral capsid
GO:0039617 T=3 icosahedral viral capsid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2c50, PDBe:2c50, PDBj:2c50
PDBsum2c50
PubMed11720290
UniProtP03612|CAPSD_BPMS2 Capsid protein

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