Structure of PDB 2c1c Chain B Binding Site BS01

Receptor Information

>2c1c Chain B (length=311) Species: 7113 (Helicoverpa zea) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNF
EDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILL
PVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIG
TSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILY
PWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYI
AGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIV
VGARRAGDLFR

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2c1c Chain B Residue 625 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2c1c Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors.
Resolution	2.3 Å
Binding residue (original residue number in PDB)	H69 E72 H196
Binding residue (residue number reindexed from 1)	H65 E68 H192
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H69 E72 R127 H196 E270
Catalytic site (residue number reindexed from 1)	H65 E68 R119 H192 E270
Enzyme Commision number	3.4.17.2: carboxypeptidase B.

Gene Ontology

	Molecular Function
GO:0004181	metallocarboxypeptidase activity
GO:0008270	zinc ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:2c1c, PDBe:2c1c, PDBj:2c1c
PDBsum	2c1c
PubMed	16260742
UniProt	Q3T905\|CBPB_HELZE Carboxypeptidase B (Gene Name=CPB)

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