Structure of PDB 2b3z Chain B Binding Site BS01

Receptor Information
>2b3z Chain B (length=359) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEEYYMKLALDLAKQGEGQTESNPLVGAVVVKDGQIVGMGAHLKYGEAHA
EVHAIHMAGAHAEGADIYVTLEPCSHYGKTPPCAELIINSGIKRVFVAMR
DPNPLVAGRGISMMKEAGIEVREGILADQAERLNEKFLHFMRTGLPYVTL
KAAASLDGKIATSTGDSKWITSEAARQDAQQYRKTHQSILVGVGTVKADN
PSLTCRLPNVTKQPVRVILDTVLSIPEDAKVICDQIAPTWIFTTARADEE
KKKRLSAFGVNIFTLETERIQIPDVLKILAEEGIMSVYVEGGSAVHGSFV
KEGCFQEIIFYFAPKLIGGTHAPSLISGEGFQSMKDVPLLQFTDITQIGR
DIKLTAKPT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2b3z Chain B Residue 1360 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2b3z Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis
Resolution2.41 Å
Binding residue
(original residue number in PDB)		H49 C74 C83
Binding residue
(residue number reindexed from 1)		H49 C74 C83
Annotation score1
Enzymatic activity
Enzyme Commision number 1.1.1.193: 5-amino-6-(5-phosphoribosylamino)uracil reductase.
3.5.4.26: diaminohydroxyphosphoribosylaminopyrimidine deaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
GO:0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
GO:0016491 oxidoreductase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0009231 riboflavin biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:2b3z, PDBe:2b3z, PDBj:2b3z
PDBsum2b3z
PubMed
UniProtP17618|RIBD_BACSU Riboflavin biosynthesis protein RibD (Gene Name=ribD)

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