Structure of PDB 2b23 Chain B Binding Site BS01
Receptor Information
>2b23 Chain B (length=233) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH
Ligand information
>2b23 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2b23
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 E76 D224 E228 M229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2b23
,
PDBe:2b23
,
PDBj:2b23
PDBsum
2b23
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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