Structure of PDB 2b1v Chain B Binding Site BS01
Receptor Information
>2b1v Chain B (length=244) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHL
Ligand information
>2b1v Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2b1v
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D234 L235 E238
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2b1v
,
PDBe:2b1v
,
PDBj:2b1v
PDBsum
2b1v
PubMed
16648639
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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