Structure of PDB 2azm Chain B Binding Site BS01
Receptor Information
>2azm Chain B (length=195) Species:
9606
(Homo sapiens) [
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TAPKVLFTGVVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCA
LGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFGFSLQDALSRA
RERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLE
Ligand information
>2azm Chain D (length=5) Species:
9606
(Homo sapiens) [
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ASQEY
Receptor-Ligand Complex Structure
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PDB
2azm
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Resolution
2.41 Å
Binding residue
(original residue number in PDB)
T1898 R1933 T1934 K1936 P2009
Binding residue
(residue number reindexed from 1)
T8 R43 T44 K46 P119
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2azm
,
PDBe:2azm
,
PDBj:2azm
PDBsum
2azm
PubMed
16377563
UniProt
Q14676
|MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 (Gene Name=MDC1)
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