Structure of PDB 1zzi Chain B Binding Site BS01

Receptor Information

>1zzi Chain B (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRI
ITITGTQDQIQNAQYLLQNSVKQYSGKFF

Ligand information

>1zzi Chain D (length=6) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ctcccc

Receptor-Ligand Complex Structure

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PDB	1zzi X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
Resolution	1.8 Å
Binding residue (original residue number in PDB)	G26 S27 I29 G30 K31 G32 I36 R40 R59 Y84 S85
Binding residue (residue number reindexed from 1)	G16 S17 I19 G20 K21 G22 I26 R30 R49 Y74 S75
Binding affinity	PDBbind-CN: Kd=2.2uM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

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Molecular Function

External links

PDB	RCSB:1zzi, PDBe:1zzi, PDBj:1zzi
PDBsum	1zzi
PubMed	16004877
UniProt	P61978\|HNRPK_HUMAN Heterogeneous nuclear ribonucleoprotein K (Gene Name=HNRNPK)

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