Structure of PDB 1zvv Chain B Binding Site BS01

Receptor Information

>1zvv Chain B (length=332) Species: 1423 (Bacillus subtilis)

MNVTIYDVAREASVSMATVSRVVNGNPNVKPSTRKKVLETIERLGYRPNA
VARGLASKKTTTVGVIIPDISNIFYAELARGIEDIASMYKYNIILSNSDQ
NQDKQLHLLNNMLGKQVDGIIFMSGNVTEEHVEELKKSPVPVVLAASIES
TNQIPSVTIDYEQAAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGY
KRALTESGLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTAIFVGTDEM
ALGVIHGAQDRGLNVPNDLEIIGFDNTRLSTMVRPQLTSVVQPMYDIGAV
AMRLLTKYMNKETVDSSIVELPHRIEFRQSTK

Ligand information

>1zvv Chain T (length=16)

ctgaaagcgcttacag

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1zvv Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
• Resolution: 2.98 Å
• Binding residue (original residue number in PDB): S15 T18 R21 N28 K30 T33 L55 A56 K58
• Binding residue (residue number reindexed from 1): S15 T18 R21 N28 K30 T33 L55 A56 K58

Gene Ontology

Molecular Function

• GO:0000976 transcription cis-regulatory region binding
• GO:0001216 DNA-binding transcription activator activity
• GO:0001217 DNA-binding transcription repressor activity
• GO:0003677 DNA binding
• GO:0003700 DNA-binding transcription factor activity
• GO:0005515 protein binding

Biological Process

• GO:0006355 regulation of DNA-templated transcription
• GO:0045892 negative regulation of DNA-templated transcription
• GO:0045893 positive regulation of DNA-templated transcription

Cellular Component

• GO:0032993 protein-DNA complex

External links

• PDB: RCSB:1zvv, PDBe:1zvv, PDBj:1zvv
• PDBsum: 1zvv
• PubMed: 16316990
• UniProt: P25144|CCPA_BACSU Catabolite control protein A (Gene Name=ccpA)