Structure of PDB 1ztz Chain B Binding Site BS01

Receptor Information
>1ztz Chain B (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGI
GGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Ligand information
Receptor-Ligand Complex Structure
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PDB1ztz From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D25 G27 A28 D29 D30
Binding residue
(residue number reindexed from 1)		D25 G27 A28 D29 D30
Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ztz, PDBe:1ztz, PDBj:1ztz
PDBsum1ztz
PubMed16227435
UniProtP03367|POL_HV1BR Gag-Pol polyprotein (Gene Name=gag-pol)

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