Structure of PDB 1zp9 Chain B Binding Site BS01

Receptor Information
>1zp9 Chain B (length=242) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDLKKIESYLDKLRIKEKDGEERKIYAEVLDGRTLKTLYKLSAKGYITAM
GGVISTGKEANVFYADGVFDGKPVAMAVKIYRIDEYLYGDERFKEKVFIW
TEKEFRNLERAKEAGVSVPQPYTYMKNVLLMEFIGEDELPAPTLVELGRE
LKELDVEGIFNDVVENVKRLYQEAELVHADLSEYNIMYIDKVYFIDMGQA
VTLRHPMAESYLERDVRNIIRFFSKYGVKADFEEMLKEVKGE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1zp9 Chain B Residue 259 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1zp9 Structure and activity of the atypical serine kinase Rio1.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		N201 D212
Binding residue
(residue number reindexed from 1)		N185 D196
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0044024 histone H2AS1 kinase activity
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006468 protein phosphorylation
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1zp9, PDBe:1zp9, PDBj:1zp9
PDBsum1zp9
PubMed16008568
UniProtO28471|RIO1_ARCFU RIO-type serine/threonine-protein kinase Rio1 (Gene Name=rio1)

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