Structure of PDB 1zky Chain B Binding Site BS01
Receptor Information
>1zky Chain B (length=245) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>1zky Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
1zky
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 L235 E238
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1zky
,
PDBe:1zky
,
PDBj:1zky
PDBsum
1zky
PubMed
16648639
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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