Structure of PDB 1zh5 Chain B Binding Site BS01

Receptor Information
>1zh5 Chain B (length=184) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKF
NRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYK
NDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIF
VVFDSIESAKKFVETPGQKYKETDLLILFKDDYF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zh5 Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		Y23 Y24 D33 F35 K54 F55 R57 L124 I140
Binding residue
(residue number reindexed from 1)		Y18 Y19 D28 F30 K49 F50 R52 L119 I135
Binding affinityPDBbind-CN: Kd=7nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1zh5, PDBe:1zh5, PDBj:1zh5
PDBsum1zh5
PubMed16387655
UniProtP05455|LA_HUMAN Lupus La protein (Gene Name=SSB)

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