Structure of PDB 1zeg Chain B Binding Site BS01

Receptor Information
>1zeg Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTDKT
Ligand information
>1zeg Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1zeg Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		C7 L11 L15 C19 R22 G23 F24 F25 T30
Binding residue
(residue number reindexed from 1)		C7 L11 L15 C19 R22 G23 F24 F25 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1zeg, PDBe:1zeg, PDBj:1zeg
PDBsum1zeg
PubMed9708987
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

[Back to BioLiP]