Structure of PDB 1zaf Chain B Binding Site BS01
Receptor Information
>1zaf Chain B (length=228) Species:
9606
(Homo sapiens) [
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LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSAMDS
SRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKG
MEHLLNMKCKNVVPVYDLLLEMLNAHVL
Ligand information
>1zaf Chain D (length=13) Species:
9606
(Homo sapiens) [
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SGSHKLVQLLTTT
Receptor-Ligand Complex Structure
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PDB
1zaf
Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
I310 K314 V328 L490 E493 V499
Binding residue
(residue number reindexed from 1)
I48 K52 V66 L218 E221 V227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1zaf
,
PDBe:1zaf
,
PDBj:1zaf
PDBsum
1zaf
PubMed
15876535
UniProt
Q92731
|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)
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