Structure of PDB 1z1b Chain B Binding Site BS01

Receptor Information
>1z1b Chain B (length=350) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELF
SGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKA
IRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIA
EGHITTNHVAATRAAKSKVRRSRLTADEYLKIYQAAESSPCWLRLAMELA
VVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMK
ETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPT
FHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
Ligand information
Receptor-Ligand Complex Structure
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PDB1z1b A structural basis for allosteric control of DNA recombination by lambda integrase.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K136 S139 V175 R176 R177 W198 K235 S274 T275 T284 Y288 Y342 R346
Binding residue
(residue number reindexed from 1)		K130 S133 V169 R170 R171 W192 K229 S268 T269 T278 Y282 Y336 R340
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008907 integrase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032359 provirus excision
GO:0044826 viral genome integration into host DNA
GO:0046718 symbiont entry into host cell
GO:0075713 establishment of integrated proviral latency

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Molecular Function
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Biological Process
External links
PDB RCSB:1z1b, PDBe:1z1b, PDBj:1z1b
PDBsum1z1b
PubMed15973401
UniProtP03700|VINT_LAMBD Integrase (Gene Name=int)

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